A Study to Determine the Role of Renal Calculi in Recurrent Urinary Tract Infections (UTI)

Overview

About this study

The purpose of this study is to describe the natural history of patients who receive treatment of non-obstructing upper urinary tract calculi on recurrent UTIs and describe the natural history of patients who chose not to receive treatment of non-obstructing upper urinary tract calculi on recurrent UTIs. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Recurrent UTIs, defined as 3 positive urine cultures of specific organisms with symptoms within 12 months (or 2 positive cultures with symptoms within 6 months) prior to clinical assessment.
  • Non-obstructing renal stone(s) on imaging within 6 months of initial visit.

Exclusion Criteria: 

  • Age < 18 years.
  • Pregnancy.
  • Hydronephrosis or evidence of obstruction.
  • Presence of a foreign body in urinary tract (e.g. Foley, ureteral stent, nephrostomy tube) at the time of UTI diagnosis.
  • Concurrent bladder calculi.
  • Urinary diversion or previous surgery involving segments of bowel interposed into the urinary tract (ileal conduit, ileal ureter etc.).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Karen Stern, M.D.

Open for enrollment

Contact information:

Karen Stern M.D.

(480) 342-3868

Stern.Karen@mayo.edu

More information

Publications

Publications are currently not available