Assessing Alterations in Carotid Blood Velocity Using Continuous Wave Doppler During Fluid Loss and Following Fluid Replacement
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 23-002922
About this study
The purpose of this study is to assess alterations in carotid blood velocity using continuous wave doppler during fluid loss and following fluid replacement.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Hemoglobin (Hgb) level > 13.0g/dl for men and > 12.0g/dl for women.
- Body weight > 110lbs.
- Blood pressure (BP) > 90/50 mmHg (systolic/diastolic).
- Blood pressure (BP) < 180 mmHg (systolic) and 100mmHg (diastolic).
- Adults over the age of 18-50 years and who are willing and able to give informed consent.
- No known diseases (i.e., cardiovascular, pulmonary, diabetes, kidney).
- Non-smokers.
Exclusion Criteria:
- Subjects underwent blood donation within 112 days.
- Hgb level < 13.0g/dl for men and < 12.0g/dl.
- Under the age of 18 or over 50 years.
- Subjects who have severe hypotension (SBP < 90mmHg).
- Subjects who have severe hypertension (SBP > 180mmHg) and/or (DBP > 100mmHg).
- Current smokers.
- Obesity (BMI > 38kg/m^2).
- Women who are known to be pregnant or plan to become pregnant within the course of this study.
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 3/17/23. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Bruce Johnson, Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available