Elderly Kidney Transplantation Immunosenescence

Overview

About this study

The purpose of this study is to assess immunosenescence in elderly waitlisted and post kidney populations and to define a senescent phenotype. The future goal would be to develop targeted cellular therapies to slow senescence or even reverse it.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 65 years.
  • Has undergone either solitary deceased or solitary living donor kidney transplantation; or
  • Waitlisted for solitary deceased or solitary living donor kidney transplantation.

Exclusion Criteria:

  • Multiorgan transplants.
  • Pregnancy.
  • Age < 65.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 7/3/23. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Lavanya Kodali, M.B.B.S., M.D.

Closed for enrollment

Contact information:

Allyson Fultz

(480) 301-6198

Fultz.Allyson@mayo.edu

More information

Publications

Publications are currently not available