Monitoring Body Composition Changes in High Risk Patients for Pancreatic Cancer (PDAC)

Overview

About this study

The purpose of this research is to monitor body composition changes with wearable devices in patients who have been identified as high risk for developing pancreatic cancer (PDAC).

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Aged 60 and over AND identified as being at high risk for PDAC at the discretion of the PI or by at least one of the following criteria:
    • 2+ relatives with PDAC on same side of family where 2 affected are first degree related to each other and at least 1 affected is first degree related to subject; age 50+ or ≤10 years younger than earliest PDAC in family at time of diagnosis;
    • 2 affected first degree relatives with PDAC; age 50+ or 10 years younger than earliest PDAC in family;
    • BRCA1, BRCA2, PALB2, ATM, MLH1, MSH2, MSH6, PMS2, EPCAM pathogenic or likely pathogenic variant AND 1 first or second degree relative with PDAC; age 50+ or 10 years younger than earliest PDAC in family;
    • Familial Atypical Moles and Malignant Melanoma (FAMMM) with pathogenic or likely pathogenic CDKN2A variant; age 40+;
    • Peutz-Jegher syndrome with STK11 pathogenic or likely pathogenic variant; age 35+;
    • Hereditary pancreatitis with PRSS1 pathogenic or likely pathogenic variant and history of pancreatitis; age 40+.

Exclusion Criteria:

  • Under the age of 60.
  • Pregnancy (to be confirmed by the patient, no pregnancy test is needed.
  • Inclusion/exclusion age increased to 60 as most high risk PDAC patients are older).
  • Individuals with pacemakers.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 9/26/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Yan Bi, M.D., M.B.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Yan Bi M.D., M.B.

(904) 953-6970

Bi.Yan@mayo.edu

More information

Publications

Publications are currently not available