Plateletworks and Teg 6s Platelet Mapping Platelet Function Assays

Overview

About this study

The purpose of this study is to compare the ability of Plateletworks Arachidonic Acid (AA) and ADP tests, and TEG 6S AA and ADP percent activity/inhibition tests, to differentiate platelet function in healthy controls and patients on dual aspirin and clopidogrel anti-platelet agent therapy.   

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • For 20 healthy controls, individuals without a history of easy bruising/bleeding who have not consumed aspirin-containing prescription or over-the-counter medications or prescription anti-platelet agents for 10 days prior to study enrollment. 
  • For the 20 volunteers in the anti-platelet agent group, 20 patients who have taken both aspirin and clopidogrel [KBMP1] on the day of study enrollment.

Exclusion Criteria: 

  • History of easy bruising/bleeding, taking over-the-counter or prescription aspirin or anti-platelet medication (group 1).
  • Not taking either aspirin or clopidogrel on the day of the study, abnormal hemoglobin or platelet count, active bleeding (group 2). 

  • Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

    Eligibility last updated 5/1/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Brooke Katzman, Ph.D.

Open for enrollment

Contact information:

Brooke Katzman Ph.D.

(507) 293-7910

Katzman.Brooke@mayo.edu

More information

Publications

Publications are currently not available