Comparing Gut Bacterial and Fungal Microbiota Profiles of Different Asthma Phenotypes

Overview

About this study

The purpose of this study is to compare the gut bacterial and fungal microbiota profiles of patients with different asthma phenotypes (eosinophilic asthma and non-eosinophilic asthma).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults ≥ 18 years of age.
  • Confirmed diagnosis of chronic asthma (mild, moderate or severe).
  • On maintenance therapy with an inhaled corticosteroid or ICS-LABA.

Exclusion Criteria:

  • Use of oral or IV antibiotic or antifungal medication within last 30 days.
  • Previous or current treatment with asthma biologic therapy (mepolizumab, benralizumab, omalizumab, or dupilumab).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/6/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Joseph Skalski, M.D.

Open for enrollment

Contact information:

Jodi Mahon

(507) 293-0694

Mahon.Jodi@mayo.edu

More information

Publications

Publications are currently not available