Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

Overview

About this study

The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

- Patient age 8-21 years..

- Diagnosis of Cerebral Palsy (standard definition of any brain injury before the age of
3) with total body involvement - any functional level

- Coronal Curve > 50 degrees on sitting film (as measured by 'greatest Cobb') OR Kyphotic
curve > 70 degrees on sitting film (as measured by T5-T12) AND

- A spinal fusion is being undertaken and the patient/family is proceeding with the
spinal fusion (with any level of distal fusion).

OR

-  A spinal fusion is not being undertaken (Non-Operative cohort) either because the family
has refused surgery or because it is not recommended at this point or surgery is
recommended but is not being undertaken because they are on a waiting list, and are being
enrolled as a non-op patient because they will be on the waiting list for > 18 months.

Exclusion Criteria:

- Previous operated scoliotic spine deformity.

- Diagnosis of Rett's Syndrome.

- Concomitant lower extremity surgery (within 3 months of spinal fusion).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 8/17/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Minneapolis, Minn.

Mayo Clinic principal investigator

Annalise Larson, M.D.

Contact us for the latest status

Contact information:

Angela Severson

(507) 538-3560

Severson.Angela2@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Annalise Larson, M.D.

Contact us for the latest status

Contact information:

Angela Severson

(507) 538-3560

Severson.Angela2@mayo.edu

More information

Publications

Publications are currently not available