Sex Differences in OSA

Overview

About this study

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated  obstructive sleep apnea (OSA).  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 20-70 years of age.

Exclusion Criteria:

  • Coronary artery disease.
  • Heart failure.
  • Pregnancy.
  • COPD.
  • Diabetes.
  • CKD.
  • Sleep disorders other than OSA.
  • Shift workers.
  • Individuals who typically go to sleep after midnight.
  • Individuals who traveled across ≥2 time zones within one week of study visits.
  • BMI ≥40.0kg/m^2.
  • Use of nicotine-containing products within the two years preceding study visits.
  • Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 8/23/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Virend Somers, M.D., Ph.D.

Open for enrollment

Contact information:

Joshua Bock Ph.D.

(507) 422-0768

Bock.Joshua@mayo.edu

More information

Publications

Publications are currently not available