Acute Modulation of Stereotyped High-Frequency Oscillations

Overview

About this study

The purpose of this study is to do data collection of EEG findings to determine whether new types analysis of intracranial EEG can add different and possibly useful information to standard types of analysis of intracranial EEG. Intracranial EEG data will be collected intraoperatively and postoperatively during routine clinical monitoring, and will be analyzed by researchers for functional brain mapping and the investigation of high frequency oscillations (HFO's), for the purpose of identifying functional and epileptogenic brain areas.  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

- patients with medically refractory epilepsy, who have been deemed appropriate
candidates for intracranial EEG monitoring

- Adult men and women (18≤ age <70 years)

- children (3≤ age <18 years)

- includes women and minorities

Exclusion Criteria:

- Subjects will be excluded if their condition makes them unable to continue with
recordings.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 2/23/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nuri Ince, Ph.D.

Open for enrollment

Contact information:

RST Neurologic Surgery Research Team

(507) 293-1963

More information

Publications

Publications are currently not available