Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder

Overview

About this study

The purpose of this study is to use upper gastro-intestinal flexible echoendoscopes in radical cystectomy specimens to determine if EUS technology can improve the staging of Urothelial Carcinoma of the Bladder (UCB). In this study, radical cystectomy specimens with urothelial carcinoma will be interrogated with echoendoscopes and EUS-guided core needle biopsies ex vivo immediately after the bladder is removed, ensuring no risk to the patient.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Undergoing radical cystectomy for confirmed or suspected urothelial carcinoma of the bladder
  • Prior abdominal imaging

Exclusion Criteria: 

  • History of partial cystectomy or complex bladder reconstruction or substitution (i.e bladder augment or urothelial recurrence in a neobladder)

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 1/28/2025. Questions regarding updates should be directed to the study team contact.
 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vidit Sharma, M.D.

Open for enrollment

Contact information:

Ekamjit Deol

Deol.Ekamjit@mayo.edu

More information

Publications

Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions