Review of Ocular Adnexal Disease

Overview

About this study

Ocular adnexal disease encompasses a wide spectrum of disorders including inflammatory, myogenic, neurogenic, and neoplastic pathology. This group of disorders affects the ocular adnexa (eyelids, orbit, extraocular muscles, and lacrimal gland) in a variety of ways but ultimately contributes to disfigurement and possible loss of vision.
In this retrospective review, we will review medical charts of patients with ocular adnexal disease. We will review patient demographics, clinical findings, laboratory findings, imaging studies, surgical records, and pathology findings. We will review these charts in attempts to elucidate clinical, laboratory, imaging, and histologic patterns in ocular adnexal disease. We will also review these medical charts to determine surgical outcomes for this spectrum of disease. Additionally, in select disease states, we may perform additional molecular-based testing on previously stored specimens to identify genomic alterations or markers of disease. Finally, a small subset of patients may be requested to submit a one-time blood draw.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • All male or female subjects of any race or ethnicity.
  • Subjects with an ocular adnexal disease including eyelid pathology or orbital disease including thyroid eye disease, orbital tumor, or other neoplastic or inflammatory condition seen at Mayo Clinic between January 1, 1990 and November 30, 2023.

Exclusion Criteria:

  • Patients diagnosed with ocular adnexal or orbital disease after this approval.
  • Incarcerated patients.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 6/24/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Andrea Tooley, M.D.

Contact us for the latest status

Contact information:

Andrea Tooley M.D.

(507) 284-2233

Tooley.Andrea@mayo.edu

More information

Publications

Publications are currently not available