Phenotype-Tailored Lifestyle Intervention for Obesity

Overview

About this study

The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Men or women between 18 to 65 years with obesity (BMI>30kg/m2).

Exclusion Criteria:

  • Weight change greater than 3% in the previous 3 months
  • History of bariatric surgery and bariatric endoscopy
  • Untreated psychiatric disorders including binge eating disorders and bulimia
  • Current use of AOMs
  • History of use of medications affecting weight or energy intake or energy expenditure in the last 6 months
  • History of type 1 diabetes mellitus or uncontrolled medical conditions (e.g., uncontrolled hypertension)
  • Women who are pregnant or plan to become pregnant
  • Any condition that limits their participation in the study
  • Principal Investigator discretion

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 01/08/2025. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Andres Acosta, M.D., Ph.D.

Open for enrollment

Contact information:

Megan Schaefer

(507) 266-6004

RSTWEIGHTLOSS@mayo.edu

More information

Publications

Publications are currently not available