Weight Loss Through Mayo Clinic Diet

Overview

About this study

The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the change in participants’ body composition and quality of life at the end of this intervention.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Males and females (non-pregnant) 18-64
  • BMI > or = to 25 kg/m2
  • Ability to read and understand English (as the Mayo Clinic Diet book and app are only available in English)

Exclusion Criteria:

  • Have a current diagnosis of melanoma or cancer diagnosis
  • Currently breastfeeding
  • Pregnant, or planned to be pregnant within 6 months
  • Have a diagnosis of Type 1 or 2 Diabetes Mellitus
  • Are taking weight loss medications or had weight loss surgery within the last year
  • Currently participating in another lifestyle weight loss program
  • Have a history of eating disorders
  • Have planned surgery in the next 6 months

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 03/042025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Tamim Rajjo, M.D., M.P.H.

Open for enrollment

Contact information:

Erin ODowd

(507) 422-9507

ODowd.Erin@mayo.edu

More information

Publications

Publications are currently not available