A Study to Gather a Database of Normal and Epilepsy Brain Scans

Overview

About this study

The purpose of this study is to build a database to do comparison studies of epilepsy patients and normal controls with Magnetic Resonance Imaging(MRI) and Electroencephalogram (EEG).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Normal Subjects Inclusion Criteria

  • Volunteers without epilepsy or CNS disease other than primary headache disorder.
  • Ages  5-55 years
  • Adult subjects able to tolerate an unsedated MRI on MR 41 (Siemens Skyra) and possibly a 2nd MRI on MR 37 (GE), and, further, possibly a 3rd MRI (one sequence only) on MR 41.
  • Pediatric subjects (5-17 years) able to tolerate an unsedated MRI on MR 37.
  • Able to tolerate a wake/sleep EEG.
  • Previously received medical care at Mayo Rochester and consents to medical information review

Normal Subjects Exclusion Criteria 

  • Prior history of seizures or epilepsy
  • Prior history of other central nervous system disease other than primary headache disorder
  • Prior intracranial surgical procedure
  • Presence of implanted devices on Radiology’s list of incompatible devices or those in which non-routine MRI processes or procedures are required
  • Chronic neck or back pain, restless legs syndrome, movement disorders, claustrophobia, or other medical problems that would interfere with the patient laying still in the scanner
  • Does not consent to review of medical information
  • Pregnancy
  • Imbedded intraorbital or scalp metallic foreign body
  • Weight greater than 300 pounds

 

Epilepsy Cases Inclusion Criteria

  • Volunteers with epilepsy
  • Ages 5-70 years
  • Adult subjects able to tolerate an unsedated MRI on MR 41 (Siemens Skyra).
  • Pediatric subjects (5-17 years) able to tolerate an unsedated MRI on MR 37.
  • Previously received medical care at Mayo Rochester and consents to medical information review

Epilepsy Cases Exclusion Criteria 

  • Prior history of other central nervous system disease other than primary headache disorder or epilepsy
  • Prior intracranial surgical procedure
  • Presence of implanted devices on Radiology’s list of incompatible devices or those in which non-routine MRI processes or procedures are required
  • Chronic neck or back pain, restless legs syndrome, movement disorders, claustrophobia, or other medical problems that would interfere with the patient laying still in the scanner
  • Does not consent to review of medical information
  • Pregnancy
  • Imbedded intraorbital or scalp metallic foreign body
  • Weight greater than 300 pounds

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jeffrey Britton, M.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Sherry Klingerman CCRP

(507)284-0451

klingerman.sherry@mayo.edu

More information

Publications

Publications are currently not available