A Study of Sex-Specific Repair Changes in the Brain Following a Concussion
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 16-009079
Sponsor Protocol Number: 16-009079
About this study
The purpose of this study is evaluate changes in male and female athletes’ brains following concussion injury and recovery, and to see whether female athletes demonstrate a different pattern of recovery compared to male athletes.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Healthy controls
- Age 16-55
- Males or females
- Patients with concussion
- Age 16-55
- Males or females
- Classification of concussion using the Ohio State University TBI identification method
Exclusion Criteria
- Healthy controls
- History of neurological disorder
- Classification of a concussion using the Ohio State University TBI identification method
- History of migraine or other headache disorder
- Tension-type headache on 3 or fewer days per month is allowed
- Gross anatomical abnormalities on T1-weighted imaging identified during routine visual inspection
- Contra-indications to MR imaging
- e.g Severe claustrophobia
- e.g Metal in the body
- Pregnancy
- Patients with concussion
- History of neurological disorder as seen clinically on MRI
- Gross anatomical abnormalities on T1-weigthed imaging identified during routine visual inspection
- Contra-indications to MR imaging
- e.g. Severe claustrophobia
- e.g. Metal in the body
- Pregnancy
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Catherine Chong, Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available