Gene Analysis in Families with Probable Inclusion Body Myositis with or without and ALS

Overview

About this study

This study proposes to identify the molecular defect in families with a clinical phenotype of “probable Inclusion Body Myositis” (“probable IBM”) but affecting  more than one family members, with or without family history of ALS.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • 10 families (2 or more siblings; one patient and a parent; 2 or more siblings and one or more blood relatives) with clinical phenotype of “probable IBM”, with or without coexisting ALS in one or more family member.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Margherita Milone, M.D., Ph.D.

Closed for enrollment

Contact information:

Margherita Milone M.D., Ph.D.

(507)266-3544

Milone.Margherita@mayo.edu

More information

Publications

Publications are currently not available