Quantitative Muscle Ultrasound – Normal values and Development of a Neuromuscular Disease Database
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 11-005337
Sponsor Protocol Number: 11-005337
About this study
The purpose of this study is to
-
To develop a database of normal values for muscle thickness and echo-intensity in American children and adults.
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To determine the sensitivity and specificity of muscle ultrasound in diagnosing neuromuscular disease in pediatric patients referred for EMG testing at the Mayo Clinic.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Children between the ages of 0 and 18 years from the Baldwin Community Pediatric clinic (well child visits as well as otherwise healthy children coming for sick child visits such as otitis media, sore throat, or cough).
- Normal adult controls will be recruited from patients referred to the Mayo EMG lab, patients or family members presenting for care in the Mayo 14 or Gonda 14 lobbies, and members of the DAHLC
- Pediatric patients referred to the SMH EMG practice for pediatric NCS and EMG under conscious sedation
Exclusion Criteria:
- History of
- Generalized pain or muscle weakness
- Diabetes mellitus or alcohol abuse
- Use of medication with known neuromuscular side effects
- Personal or family history of generalized neuromuscular disease such as myopathy, dystrophy, anterior horn cell disease, or length-dependent peripheral neuropathy
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Andrea Boon, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available