Gastrointestinal Lewy Bodies: A Cause or Effect of Parkinson’s Disease?
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 15-005408
Sponsor Protocol Number: 15-005408
About this study
The purpose of this proposal is to explore whether the presence of Lewy pathology in the gastrointestinal tract is associated with functional disturbances such as constipation and dysphagia in both Parkinson’s disease patients and non-Parkinson’s disease patients, and if present in the latter patients whether this relates to the subsequent development of Parkinson’s disease.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age 18 years or older
- Able to provide informed consent
- Resident of the United States (to make it possible to conduct future subject follow-up using the National Death Index)
- Undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation
Exclusion Criteria:
- Patients not undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation
- Patients with bleeding disorder
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator Kenneth DeVault, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available