Clinical Trials

Inclusion Criteria:

• Age 18 to 70 years old.
• Diagnosis of opioid use disorder.
• Stable dose of buprenorphine or naltrexone for 7 days.
• No pharmacotherapy for OUD for 7 days for individuals in the no pharmacotherapy group.

Exclusion Criteria

• Medical or surgical conditions that could be adversely impacted by HP testing including, but not exclusively limited to, active psoriatic lesions at the site of testing, cellulitis at site of testing, and previous skin grafting at site of testing. Patients may be excluded for other comorbid medical or surgical conditions based on the physician investigator’s discretion.
• History of schizophrenia, dementia, or other chronic psychiatric disorder that could be adversely impacted by study participation. Patients may be excluded for other comorbid mental health conditions based on the physician investigator’s discretion.
• Inability to function independently in an ambulatory care setting due to severe deconditioning requiring use of supportive gait aids including a cane or walker.  Patients may be excluded for other functional problems based on the physician investigator’s discretion.
• Signs and symptoms of opioid withdrawal syndrome.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/14/2024. Questions regarding updates should be directed to the study team contact.