Inclusion Criteria:

• Outpatients with rheumatoid arthritis defined by American College of Rheumatology 2010 criteria.
• Patients whose biologic therapy with Humira has been prescribed by their physician[AAM1]  as standard of care, after failure or incomplete control of disease with at least 3 months therapy with methotrexate or other oral immunomodulators[AAM2].
• Adults between 18-80 years of age.
• Ability to provide informed consent.
• Ability to understand English either personally or through a translator.

Exclusion Criteria:

• Outpatients with rheumatoid arthritis who have not been prescribed Humira by their physician as standard of care.
• Patients younger than 18 years of age or older than 80 years of age.
• Patient’s unable to provide informed consent.
• Patients unable to understand English either personally or through a translator.
• Patients who are pregnant or breast-feeding.
• Patients with rheumatoid arthritis who are stable on current therapy with Humira, as prescribed by their physician as standard of care.
• Patient has already begun taking Humira prescribed by physician as standard of care before screening/baseline visit.