A Study to Evaluate Home-Based Exercise as an Intervention for Treating Patients with Varying Levels of Kidney Function
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 20-009666
NCT ID: NCT04745169
About this study
The purpose of this research is to to determine whether home-based cardiac rehabilitation (CR) is an effective intervention to improve decreased physical function in patients with varying levels of kidney function. We will determine if home-based CR improves frailty parameters and SPPB scores. We will also determine if home-based CR improves health-related quality of life (HRQOL), body composition, physical activity, and adverse outcomes, including hospitalizations and death.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age 18 years or older.
- Consenting to research.
- Chronic kidney disease (stages 1-5).
- An SPPB score ≤ 10 or considered frail or pre-frail according to the Fried Frailty Phenotype.
Exclusion Criteria:
- Younger than 18 years.
- Patients being evaluated for combined organ transplantation.
- Significant comorbidities that limit rehabilitation potential including pulmonary disease requiring continuous oxygen supplementation, active angina, critical aortic sclerosis, decompensated heart failure, or known ventricular arrhythmia.
- An SPPB score > 10 or not considered frail or pre-frail by the Fried Frailty Phenotype.
- Non-English speaker without availability of adequate interpreter services (safety concern).
- Failure to pass submaximal exercise test in pateints not approved for kidney transplantation at our center.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Cassie Kennedy, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available