Mayo Clinic Study of Aging – Jacksonville

Overview

About this study

The purpose of this study is to advance the study of normal and pathological aging in a representative cohort of participants within Jacksonville and surrounding area, including participants from people groups who are often underrepresented in research studies. These goals will be accomplished by obtaining comprehensive measures of cognitive and physical health participants, paired with established and non-invasive blood-based biomarkers. Access to non-invasive measures of common age-related pathology (e.g., Alzheimer and cerebrovascular disease) would disproportionately benefit Black and Hispanic community members who are routinely under-represented in biomarker-based studies requiring PET neuroimaging or cerebrospinal fluid sampling.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:             

  • Community-dwelling.
  • Age ≥ 45 years (no upper limit).
  • Cognitively normal at study entry (CDR = 0).

Exclusion Criteria:

  • Individuals with cognitive impairment.
  • Individuals with neurological diseases that may affect cognition such as epilepsy, multiple sclerosis, severe head injury, motor neuron disease, Parkinson disease.
  • Individuals with psychiatric diseases that could affect cognition or longitudinal participation, including bipolar disorder, schizophrenia, uncontrolled depression or anxiety.
  • Individuals with medical illnesses that would prevent them from participating in a longitudinal study such as active cancer, significant heart, lung, kidney and other system illness.
  • Individuals chronically using medications likely to affect cognition (e.g., scheduled narcotics).

Eligibility last updated 11/5/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Gregory Day, M.D.

Open for enrollment

Contact information:

Memory Disorder Clinic

(904) 953-2677

More information

Publications

Publications are currently not available