Patient Adherence and Symptoms During Post-operative Fluid Restriction Protocol After Transsphenoidal Surgery

Overview

About this study

The objectives of this study are to survey patients during the post-operative period regarding their experience with fluid restriction including adherence and discomfort, and to document rates of hyponatremia and readmissions in post-operative patients.

Advances in endonasal, endoscopic transsphenoidal surgical techniques have decreased complications and length of stay for persons undergoing resection of sellar and suprasellar masses  Previous research by investigators now at Mayo (SLS, AQH) has shown that particular interventions including fluid restriction post-operatively decrease patient morbidity (e.g., from hyponatremia) and readmissions while maintaining patient safety. However, the patient perspective on the impact of fluid restriction has not been documented.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Critieria:

  • All adult (18- 90 years of age) patients.
  • Undergoing endonasal, endoscopic transsphenoidal surgery.
  • The lesions can include neoplasms: pituitary adenomas, craniopharyngiomas, arachnoid cysts, epidermoid cyst, pituicytomas, meningiomas, optic gliomas, metastatic carcinoma.
  • Other infiltrative disorders: hypophysitis, abscesses, Langerhans cell histiocytosis, etc.

Exclusion Criteria:

  • Patients who have post-operative diabetes insipidus or pre-existing diabetes insipidus.

     

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Susan Samson, M.D., Ph.D.

Open for enrollment

Contact information:

Aleeshba Basil

Basil.Aleeshba@mayo.edu

More information

Publications

Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

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