Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

Overview

About this study

The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Women ≥ 18 years of age and ≤ 80 years of age.
  • Have diagnosis of symptomatic uterovaginal prolapse.
  • Have elected to undergo surgical management of uterovaginal prolapse after consultation with their physician.
  • Are eligible for both minimally invasive supracervical hysterectomy with sacrocolpopexy (MI-SCH+SCP) and total vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS).

Exclusion Criteria:

  • Patients who wish to undergo uterine sparing procedures.
  • Body mass index BMI) > 50.
  • Previous hysterectomy or prior uterovaginal surgery.
  • Have a diagnosis of neurogenic bladder, Parkinson's disease, multiple sclerosis, spinal cord injury, or cerebrovascular accident.
  • Chronic indwelling urinary catheter.
  • Urinary diversion of any type.
  • Any condition or disorder that, in the opinion of the investigator, might prevent the subject from completing the study or interfere with the interpretation of the study results.
  • Unable to speak, read, understand English.

Eligibility last updated 6/6/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Sherif El Nashar, M.B., B.Ch., M.S.

Open for enrollment

Contact information:

Sherif El Nashar M.B., B.Ch., M.S.

(904) 953-2979

premierstudyteam@mayo.edu

More information

Publications

Publications are currently not available