Inclusion Criteria:

• Healthy adult males and females.
• Between the ages of 40 and 60.
• Provides consent to participate in the study.
• Understands and agrees to follow all study procedures and limitations.

Exclusion Criteria:

• Pregnant, nursing, or trying to conceive.
• BMI restrictions: < 30.
• Allergy or sensitivity to study agent ingredients.
• Hypertension treated with medication.
• Use of natural health products containing nicotinamide riboside, quercetin, trans-resveratrol, or betaine anhydrous within 7 days prior to randomization and during the course of the study. 
• Surgery planned during the course of the trial.
• History or past diagnosis of chronic diseases, unstable medical conditions, blood/bleeding disorders or stroke.
• History or current diagnosis of cancer (except for successfully treated basal cell carcinoma diagnosed less than 5 years prior to screening or cancer in full remission more than 5 years after diagnosis.
• Abnormal blood chemistries for renal or liver function (defined as 1 standard deviation outside of the normal range), alcohol dependence, uncontrolled thyroid disease, severe obesity (body mass index > 40 kg m^2), or weight stable for at least 3 months prior to enrolling in the study (defined as > 2 kg change in body mass).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/25/23. Questions regarding updates should be directed to the study team contact.