Ultrasound Perfusion Estimation for assessment of Peripheral Arterial Disease

Overview

About this study

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the response to interventional treatment in PAD patients.  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patient volunteers, Male and Female, ages 18 years old and up with symptom of claudication and suspected for PAD who are scheduled for vascular testing.
  • Healthy volunteers, Male and female, ages18 years old and up who have normal BMI and do not have any history of smoking, cardiovascular disease, diabetes.

Exclusion Criteria: 

  • Patients’ volunteers:  Patients with gangrene, patients having surgery or stent or having ulcer on their leg or any health condition that does not allow proper use of ultrasound scanning, and people considered in “vulnerable” populations.
  • Healthy volunteers: Volunteers include BMI above 25, no history of smoking, no history of (diabetes, hypertension, cardiovascular diseases) and people considered in “vulnerable” populations.

Aim 2:

The study group will include N=100 patients diagnosed with PAD.

Inclusion Criteria:

  • Female and male volunteers, ages 18 and up, who have been diagnosed with PAD and are scheduled for treatment (lifestyle change or interventional treatment).

Exclusion Criteria:

  • Patients with Gangrene, Patients having surgery, having ulcer on leg or any health condition that does not allow proper use of ultrasound scanning and people considered in “vulnerable” populations.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 3/11/2024. Questions regarding updates should be directed to the study team contact.

 

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Azra Alizad, M.D.

Contact us for the latest status

Contact information:

Azra Alizad M.D.

(507) 538-1727

Alizad.Azra@mayo.edu

More information

Publications

Publications are currently not available