Molecular Analysis to Drive Individualized Care in Lung Cancer
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 24-000609
Sponsor Protocol Number: 24-000609
About this study
The purpose of this study is to determine if robotic biopsies provide sufficient material for whole genomics and transcriptomics, transcriptome anomalies are confined to tumor cells as opposed to background lung parenchyma, and whole genomics may provide further pathologic insight in cases where de novo primary may be difficult to discern from metastatic disease.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Subject age 18 years and older.
- Subject is suitable for elective bronchoscopy.
- Subject with a moderate to high risk of lung cancer based on clinical, demographic and radiologic information or with suspected metastatic disease.
- Ability to provide blood or saliva sample.
- Enrolled in study IRB#16-009655.
- Ability to provide archived tissue.
- Subject is able to understand and adhere to study requirements and able to provide informed consent.
Exclusion Criteria:
- Individuals who have situations that would limit compliance with the study requirements.
- Institutionalized (i.e., Federal Medical Prison).
- Prior germline genetic testing with a 40+ multi-gene panel within the last 1 year of enrollment; AND/OR
- Prior somatic tissue (250+ gene) testing within the prior 3 months of enrollment.
- Of note: Women, who are pregnant, or planning to become pregnant, can take part in this study.
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 1/12/24. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
Contact |
Rochester, Minn.
Mayo Clinic principal investigator Janani Reisenauer, M.D. |
Open for enrollment |
Contact information:
Cancer Center Clinical Trials Referral Office
(855) 776-0015
|
More information
Publications
Publications are currently not available