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A Study to Evaluate Intralesional Injection of Triamcinolone Acetonide to Treat Desmoid Tumors
No Locations
The purpose of this study is to determine the response of desmoid tumors to intralesional injections of triamcinolone acetonide.
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A Study of Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
Jacksonville, FL; Rochester, MN
The NIR-DT-301 Phase 3, double-blind, placebo-controlled study is being conducted to determine the efficacy, safety, and tolerability of nirogacestat in participants with progressing desmoid tumors.
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Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis
Jacksonville, FL; Rochester, MN
This randomized phase III trial compares the effects, good and/or bad, of sorafenib tosylate in treating patients with desmoid tumors or aggressive fibromatosis. Sorafenib tosylate may stop the growth of tumor cells by blocking some of the proteins needed for cell growth.
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A Study to Evaluate AL102 to Treat Patients with Progressing Desmoid Tumors
Scottsdale/Phoenix, AZ; Jacksonville, FL; Rochester, MN
The purpose of this study is to evaluate the effectiveness and safety of AL102 in patients with progressive desmoid tumors.
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Study of E7386 in Participants With Selected Advanced Neoplasms
Scottsdale/Phoenix, AZ; Jacksonville, FL; Rochester, MN
The purpose of this study is to assess the safety/tolerability profile of E7386 as a single agent administered orally in participants with selected advanced or recurrent neoplasms and to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of E7386.