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Analysis of the Mid-Upper Gastrointestinal Tract in Adults
Rochester, MN
The purpose of this study is to find more information about the bacteria that live in the gastrointestinal tract. Bacteria are essential for human life; they are needed to digest food, break down certain vitamins and form a barrier against disease-causing bacteria. We are doing this research study to understand the relationship between bacteria (the human microbiome) and their role in health and disease.
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A Study to Assess the Added Value of CTA in the Algorithm for Management of Acute Lower GI Bleeding
Rochester, MN
The purpose of this study is to determine the value of CTA as a first-line diagnostic study in hemodynamically stable patients who present to the emergency room with signs of lower GI bleeding that will undergo colonoscopy with bowel preparation.
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Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device (VAD) Patients
No Locations
The purpose of this study is to estimate the proportion of Ventricular Assist Device (VAD) patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood test. Also, in patients with gastrointestinal bleeding present, to summarize the extent of gastrointestinal bleeding; to examine the behavior of HemoQuant fecal occult blood test over time by estimating the proportion of VAD patients with a positive test prior to implantation; at one week, one month, three months, six months and one year post implantation, and after explantation of the VAD and to evaluate whether presence of any abnormal fecal HemoQuant test is ...
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A Study to Evaluate the Safety, Tolerability, and Clinical Benefit of AK002 in Adult Patients with Mast Cell Gastritis and/or Gastroenteritis
Rochester, MN
The purpose of this study is to evaluate the safety and tolerability of AK002 in patients with mast cell gastritis and/or gastroenteritis, examine changes in number of mast cells/HPF in gastric and duodenal biopsies, examine any change in gastrointestinal symptom score as estimated by a daily patient-reported outcome (PRO) questionnaire and look for any changes in absolute peripheral blood eosinophil counts.
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A Study to Detect Upper Gastrointestinal Bleeding Using a Bleeding Sensor Pill
Rochester, MN
The objective of this study is to evaluate the feasibility of detecting blood in the stomach of a patient with suspected Upper Gastrointestinal Bleeding (UGIB).
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A Study of Pharmacogenomics Testing in Patients Who Experience Bleeding While on Apixaban or Warfarin
Scottsdale/Phoenix, AZ
The purpose of htis study is to see if PGx testing will help to determine better ways for doctors to use apixaban treatment.
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Collection of Tissue, Blood Samples, and/or Cystic Fluid in Patients with Benign, Premalignant and/or Malignant Gastrointestinal (GI) Disease
Scottsdale/Phoenix, AZ
The goal of this study is to establish and maintain a gastrointestinal disease biospecimen bank containing samples of neoplasms, normal tissue, blood and/or any other tissue or cystic fluid from patients undergoing a diagnostic or therapeutic procedure for gastrointestinal disease.
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A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
Rochester, MN
The objective of this study is to compare the safety, tolerance and efficacy of BLI800 to a PEG based preparation prior to colonoscopy in adolescent patients.
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International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project
Rochester, MN
The purpose of this study is to identify the clinical characteristics, the management and the outcomes of acute kidney injury (AKI) in patients with cirrhosis worldwide. Additionally, to establish the severity of AKI across different regions, to identify precipitants of AKI across different centers, to identify the phenotypes of AKI across different centers, to evaluate differences in the management of AKI across different centers and their impact on clinical outcomes, and to assess outcomes of acute kidney injury (resolution of AKI, in-hospital mortality, 28-day mortality, 90-day mortality).