Clinical Trials

Hypothermia

Displaying 2 studies

  • A Study of the Prevalence and Characteristics of Multiple Sclerosis Related Hypothermia Rochester, MN

    The aims of this study are:

    • To assess the prevalence of episodic hypothermia among multiple sclerosis (MS) patients evaluated at Mayo Clinic.

    • To characterize clinical, radiographic, and laboratory features of patients with MS-related hypothermia.

  • Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest Rochester, MN

    ILCOR guidelines recommend Target Temperature Management (TTM) to between 32°C and 36°C after out-of-hospital cardiac arrest, based on low quality evidence. In a previous trial, TTM at 33°C did not confer a survival benefit or improved neurological function, compared to TTM at 36°C. A lower target temperature might be beneficial compared with normothermia and early treatment of fever. Therefore the primary purpose of the TTM2-trial will be to study any differences in mortality, neurological function and quality of life between a target temperature of 33°C and standard care avoiding fever.

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