-
A Study of the Safety, Tolerability and Effectiveness of Eleclazine on Shortening the QT Interval in Adults with Long QT-3 Syndrome
Rochester, MN
The purpose of this study is to evaluate the safety, tolerability and effectiveness of eleclazine for shortening the corrected QT interval in adults with type 3 long QT syndrome.
-
A Study of the Clinical Phenotype of Patients Seen in Mayo's Genetic Heart Rhythm Clinic (Prospective)
Rochester, MN
The purpose of this study is to obtain full phenotypic information on all patients diagnosed with Congenital Long QT Syndrome and seen in the Mayo Clinic Long QT Clinic.
-
A Study to Assess the Current FDA-approved AliveCor Kardia Device to Measure the QT/QTc in Patients Presenting to the Genetic Heart Rhythm Clinic
Rochester, MN
The purpose of this study is to assess the feasibility of using the current FDA-approved AliveCor Kardia device and their AliveCor Tripod device (FDA Approval pending) to measure the QT/QTc in patients presenting to the Genetic Heart Rhythm Clinic.
-
Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care
Rochester, MN
The purpose of this study is to further develop and evaluate a diagnostic procedure suitable for use in an inexpensive diagnostic instrument suitable for screening for Long QT Syndrome (LQTS) in the primary care environment.
-
A Study for the Development of a Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care
Rochester, MN
The purpose of this study is to specify, develop, and evaluate a diagnostic algorithm suitable for use in an inexpensive diagnostic instrument suitable for screening for LQTS in the primary care environment.
-
Genetic Variants in Medication-Induced Torsade de Pointes
Rochester, MN
The purpose of this study is to determine if common genetic variants that underlie the QT interval are also associated with medication-induced torsade de pointes (TdP).
-
Exercise in Genetic Cardiovascular Conditions
Rochester, MN
The goal is to determine how lifestyle and exercise impact the well-being of individuals with hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS).
-
"About Me" Pedigree Tool Pilot
Rochester, MN
The objective of this study is to determine the utility and accuracy of patients utilizing the About Me pedigree tool to create their own pedigrees for use in risk assessment in a cardiovascular genetics clinic.
-
Prospective Identification of Long QT Syndrome in Fetal Life
Rochester, MN
The postnatal diagnosis of Long QT Syndrome (LQTS) is suggested by a prolonged QT interval on 12 lead electrocardiogram (ECG),a positive family history and/or characteristic arrhythmias and confirmed by genetic testing. LQTS testing cannot be performed successfully before birth as fetal ECG is not possible and direct measure of the fetal QT interval by magnetocardiography is limited. Genetic testing can be performed in utero, but there is risk to the pregnancy and the fetus. Although some fetuses present with arrhythmias easily recognized as LQTS (torsade des pointes (TdP) and/or 2° atrioventricular (AV) block, this is uncommon, occurring in <25% of fetal ...