Clinical Trials

Rumination is an upper gastrointestinal (GI) disorder characterized by the frequent regurgitation of recently ingested food. Very little is understood about the nature and treatment of this disorder. The act of regurgitation in rumination involves the opening of the upper esophageal sphincter and the muscular contraction of the abdomins rectus. Behavioral treatment of these symptoms is the clinical intervention of choice; however, only uncontrolled case documentation exists to support its effectiveness. However, an effective behavioral mechanism may be relaxation of the muscles. From a behavioral standpoint, muscular relaxation is incompatible with the necessary muscular contraction for rumination.

To date, single case ...

The purpose of this study is to:

1. Assess spectrum of symptoms among patients with rumination syndrome diagnosed at Mayo Clinic (through interviews with previously diagnosed patients);
2. Assess the quality of life in persons with rumination syndrome (through interviews with previously diagnosed patients); and
3. Develop a symptom scoring tool which can be used to assess outcomes and response to therapy in this group