Clinical Trials

Small fiber neuropathy

Displaying 2 studies

Intra-epidermal Nerve Fiber Densities (IENFDs): A Study of Olmsted County Inhabitants and Surrounding Area, Including Normal Subjects, Patients with Neuropathy or Impaired Glucose and Newly Diagnosed Diabetics Rochester, MN

This is a study of nerve fibers to the skin of your body, counts of which are used to determine disease of nerves called "small nerve fiber neuropathy." Counting nerve fibers of a small sample of skin gives an indication of whether the numbers of these fibers are normal or decreased. A decreased number is an indication of abnormality, that is, of disease of small nerve fibers (small fiber sensory neuropathy). This study, therefore, may be useful in diagnosing small fiber sensory neuropathy in people who have diabetes mellitus and other diseases. Skin samples will be used to determine what is ...
The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream Rochester, MN

This is a study of epidermal (the outer most layer) nerve fibers (ENFs) in the skin of the body; counts of which are used to determine a disease of nerves called "small nerve fiber neuropathy."

Capsaicin is approved by the Food and Drug Administration (FDA) for pain relief. Since 0.1% capsaicin is known to cause ablation (removal) of ENFs, this study will test whether such ablation results in relief of spontaneous pain, touch, or heat-pain.