Clinical Trials

This randomized, double-blind, placebo-controlled, multicenter, confirmatory study will evaluate the efficacy and safety of Cook MyoSite Incorporated Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) compared to a placebo (vehicle) control dose in the treatment of stress urinary incontinence (SUI) in adult female patients.

Does a twice weekly, 12-week Pilates pelvic floor strengthening program improve short- and long-term measures of stress urinary incontinence symptoms in women ages 45-70 years of age?

GTx-024 is an orally bioavailable and tissue-selective nonsteroidal selective androgen receptor modulator (SARM) that has demonstrated androgenic and anabolic activity and is currently being evaluated as a potential treatment for stress urinary incontinence (SUI) in postmenopausal women. Urinary incontinence and pelvic floor disorders are major health problems for women, especially as they age. Pelvic floor muscle relaxation has been found to correlate with lower urinary tract symptoms including SUI. Muscles of the pelvic floor and lower urinary tract are crucial for supporting the pelvic organs and micturition; however, damage to the muscles or lack of hormonal stimulation are thought to ...

The purpose of this study is to examine correlations between stress urinary incontinence (SUI) severity and running cadence and asymmetry/performance on the 30s sit-to-stand test (SLSTS30sec) in post-partum women with SUI.

The purpose of this study is to define the successful placement of the Artificial Urinary Sphincter in Men, by collecting and comparing patient subjective and objective assessment data. 

The purpose of this study is to create a Mayo Clinic AUS research database with follow-up through 4 months.  To eventually evaluate other risk factors for AUS complications, including prior treatments, comorbidities and obesity.

Concurrent treatment of endometrial cancer and SUI may improve QOL, emotional and physical health and decrease costs for both patients and the health care system. At the time of endometrial cancer diagnosis, not only are women evaluated by a gynecologist and/or a gynecologic oncologist, but the majority will undergo surgery within weeks of their diagnosis. Thus, urinary incontinence could easily be identified, a referral made, and concurrent surgery performed. This would spare the patient two surgeries, decrease the emotional distress associated with SUI symptoms, decrease the costs associated with SUI for the patient and possibly improve overall quality of life. ...

The purpose of this research study to help us understand whether a type of ultrasound can measure bladder stiffness (or compliance).

The purpose of this study is to assess if men and women seeking care for urological diseases have interest in support services in conjunction with standard of care.