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A Study Comparing Rigid Removable Dressing Systems for Improving Healing and Activity Levels Following Lower Leg Amputations
Rochester, MN
The purpose of this study is to compare different rigid removable dressing systems that are used to heal and protect a limb following an amputation by measuring the healing of the surgical incision and the activity level of patients following surgery.
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A Study of Mesenchymal Stem Cell (MSC) Adherence and Vessel Wall Penetration Following Intra-arterial Delivery Subsequent to Controlled Balloon Angioplasty
Jacksonville, FL
The purpose of this study is to determine the amount of MSCs that adhere to predetermined areas of arterial wall following balloon angioplasty vs no intervention, and to characterize the effect of intra-arterial injection of MSCs on predetermined areas of arterial wall via transcriptome analysis.
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ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial
Rochester, MN
The primary objective of the study is to demonstrate that anticoagulation with bivalirudin results in fewer major bleeding complications compared with unfractionated heparin (UFH) in subjects undergoing peripheral endovascular interventions (PEI). The secondary objective is to identify potential benefits from bivalirudin therapy on other clinically important events such as death, myocardial infarction (MI), stroke and/or transient ischemic attack (TIA), amputation, unplanned repeat revascularization (URV), and minor bleeding, as well as potential economic benefits that may result from improved clinical outcomes.
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Myoelectric SoftHand Pro to Improve Prosthetic Function for People With Below-elbow Amputations: A Feasibility Study
Rochester, MN
A study to investigate the hypothesis that a Pisa/IIT Robotic SoftHand Pro converted to a prosthetic terminal device will enhance the performance of people with limb loss in a wider range of daily living tasks than allowed by today's commercially available prosthetic hands, and will exceed established benchmarks for activities of daily living (ADL).
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Characterization of Degenerative Tendons
Rochester, MN
The purpose of this investigation is to identify changes in tendon composition and gene expression between diseased and non-diseased tendon tissue with the goal of identifying molecular targets that can be harnessed to treat or reverse degenerative tendon disease.