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Endurant Stent Graft System vs Excluder Endoprothesis: A Global, Prospective, Randomized Clinical Trial in Sac Regression (ADVANCE Trial)
Jacksonville, FL
The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysms. Subjects will be randomized and imaging will be collected at all follow-up time points to assess the primary endpoint.
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A Study to Evaluate the Effectiveness of Nicotinamide Riboside and Pterostilbene Treatment to Protect the Kidneys in Patients with Complex Aortic Aneurysm Repair and Aortic Arch Reconstruction
Rochester, MN
The purpose of this study is to determine the effectiveness of Basis™ (Nicotinamide Riboside and Pterostilbene) in preventing acute kidney injury (AKI) among patients undergoing complex aortic aneurysm repair and aortic arch reconstruction.
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A Study to Evaluate the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis to Treat Thoracoabdominal and Pararenal Aortic Aneurysms
Scottsdale/Phoenix, AZ
The purpose of this study is to assess the safety and effectiveness of the TAMBE Device in the treatment of thoracoabdominal and pararenal aortic aneurysms.
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Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
Rochester, MN
Prospective, non-randomized, , multicenter study with two independent arms:
* Primary Study Arm - TAAA and Pararenal aneurysms requiring only TAMBE System. Hypothesis-driven analysis.
* Up to 65 additional subjects may be implanted in Continued Access Phase under the Primary Study Arm only
* Secondary Study Arm - TAAA requiring TAMBE System and CTAG Device(s). Non hypothesis-driven analysis.
Minimum: 122 implanted subjects. Maximum: 202 implanted subjects with up to 65 additional subjects implanted in Continued Access (Primary Study arm)
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A Study to Assess Temporal Changes in Reintervention Rate and the Impact of Reinterventions after Endovascular Aortic Repair (EVAR)
Rochester, MN
The purposes of this study are to determine temporal changes in patient reported outcomes and quality of life (QOL) associated with EVAR, factors associated with requirement for reintervention after EVAR, and the effect of reinterventions on patient reported outcomes and QOL associated.