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Clinical Trial to Evaluate the PrevisEA Device for Predicting Gastrointestinal Impairment
Rochester, MN
The purpose of this research is to study the performance of a device called PrevisEA, an investigational device not approved by the Food and Drug Administration (FDA). This research is sponsored by the maker of the PrevisEA device, Entac Medical Inc. This device listens to and records abdominal sounds which provides data that can help predict gastrointestinal impairment (GII). GII is a condition that is defined as the failure of oral re-feeding after abdominal surgery.
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Colorectal Resection in Emergency General Surgery
No Locations
The purpose of this study is to define the early postoperative morbidity and mortality of EGS patients undergoing colon resection in the urgent/emergent setting, with a specific focus on the comparison of patients undergoing colonic anastomosis versus diversion.
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A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis
Scottsdale/Phoenix, AZ; Jacksonville, FL
This is a proof-of-concept study to evaluate the preliminary clinical activity of guselkumab in subjects with Familial Adenomatous Polyposis. The study is designed to determine if guselkumab has clinical activity in the colorectum and duodenum, by reducing the number of polyps over a period of 24 weeks.
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Comparison of the Diagnostic Accuracy of Fujifilm Endoscopic Hypoxia Imaging (FEHI) to Indocyanine Green Fluorescein Imaging in Assessing Intraoperative Tissue Ischemia in Gastrointestinl Surgery
Jacksonville, FL
The aims of this study are to compare the diagnostic accuracy of FEHI, a non-invasive, non-drug, spectral imaging technology to current standard of care, ICG fluorescein imaging, with regard to intraoperative tissue ischemia, to estimate the optimal threshold value for SpO2 in FEHI to achieve optimal correlation with ICG imaging, and to compare the time needed to complete FEHI compared to ICG. These will be compared in the final 70% of cases to avoid learning curve bias on the first cases.
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Post-Surgical Based Efforts to Reduce Preventable Readmissions and Optimize Length of Stay
Rochester, MN
The investigators believe that the lessons learned from studies regarding 30-day and 90-day readmission are primarily due to failure of early symptom recognition, and medical error. Through the aid of remote monitoring and early symptom detection, the hypothesis for the current proposal is that interventions can be recommended in an earlier, remote fashion that may result in earlier post-surgical discharge, prevent decompensation, and prevent increased readmissions that have been associated with decreased LOS in other surgical populations.