Clinical Trials

The purpose of this study is to provide educational community outreach  seminars on wellness and exercise for individuals living with a neurological physical disability and to measure the effects of these seminars for them and their care givers (family, therapists, community personal trainers and community funders such as Lions or Rotary Clubs).

We are doing this study to compare how acute maximal and acute endurance exercise affect immune cell populations in the blood for different populations of healthy participants (comparing age, gender, fitness level, etc). We hope to use this information to develop a baseline understanding of how exercise affects immune system function.

The purpose of this study is to assess whether a daily, 15-minute stretching routine for one year reduces musculoskeletal pain and improves quality of life in personnel working in the radiology and cardiology departments ata Mayo Clinics and Mayo Clinic Health System sites.

The objectives of this study are to assess the ‘longer-term’ clinical, pulmonary, cardiac, functional, and psychosocial sequelae of COVID-19 survivorship, and to investigate whether exercise therapy enhances recovery of and/or improves pulmonary and cardiac function, exercise capacity, clinical status, and overall HRQoL in COVID-19 survivors.

This study will assess the effect of incorporating a tonal exercise device into clinical and chiropractic care for lower back pain. 

The purposed of this study are to investigate whether structured exercise training improves cardiac and pulmonary haemodynamic function, exercise capacity, and short-term clinical outcomes in heart failure (HF) patients with Pulmonary Hypertension (PH), and to develop a multivariable exercise pulmonary gas exchange ‘score’ that accurately differentiates HF patients with pre- and post-capillary PH (CpcPH) from HF patients with isolated post-capillary PH (IpcPH).

This research is intended to begin to explore the impact of inspiratory muscle resistance exercise and/or 1,25(OH)2D3 for improving respiratory muscle strength in cancer patients (subjects).

The aim of the study is to investigate the effects of a 3-month resistance exercise program (in people aged 50 to 75) on muscle mass, body composition, muscle strength, brain function and cognition, muscle efficiency processing blood sugar, the body’s ability to build muscle, and fat cells.

Earlier research has shown that exercise has significant benefits in preventing certain diseases and conditions such as diabetes, dementia, heart disease, and more. We also know from other research that resistance exercise (lifting weights) and aerobic exercise (running, biking, walking), improve metabolism through separate ways on the molecular level, also called “molecular pathways.” With ...

The purpose of this study is to produce preliminary data testing the feasibility and effectiveness of high intensity interval training (HIIT) on cardiovascular health parameters in individuals with paraplegia.

The purpose of this study is to seek and identify the mechanistic underpinnings of the effects of resistance exercise (RE) on insulin sensitivity.

The purpose of this study is to:

Aim 1. To assess the receptivity of the robotic human trainer technology for potential delivery of exercise coaching.

Aim 2. To explore differences on receptivity of the robotic human trainer technology by sex, age, smoking status, perceived weight.

Aim 3. In addition to the survey, we will obtain qualitative feedback through focus groups on receptivity and potential deployment of the technology for exercise coaching among adolescents.

The purpose of this study is to test the feasibility of a Digital Home-Exercise Therapy Application (DETP) by conducting a randomized, controlled, non-inferiority study to compare the DETP to conventional physical therapy (PT).

This study hypothesises that physical exercise in children with epilepsy will be associated with a significant reduction in interictal spikes and a significant reduction in spike burden.

This study aims to determine if vigorous physical exercise results in significant increases or reductions in spike frequency in children on continuous video EEG monitoring.

The purpose of this study is to examine the effect of a structured pre-athletic event cervical muscle warm-up program on cervical muscle performance.

The main purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen. The two approaches of the same total exercise durston will include: 1) HIIT with progressively increased interval durations (PRO-HIIT) versus 2) HIIT with constant shorter interval durations (CON-HIIT). The study hypothesis is that the progressively increased interval duration at high-intensity (PRO-HIIT) will result in a greater increases in fitness, heart function, and the ability of the body's muscles to receive oxygen in patients enrolled in cardiac rehabilitation. 

The purpose of this study is to conduct a clinical trial examining the preliminary effectiveness, feasibility, and acceptability of an exercise intervention on frailty after kidney transplantation (KT).

The purpose of this study is to determine if epidural spinal cord stimulation can affect blood pressure control and blood vessel resistance during exercise in heart failure patients by intercepting messages of muscle fatigue and shortness of breath.

The purpose of this study is to develop a data-driven approach that enables healthcare providers to “prescribe” exercise in the appropriate dose in a manner analogous to prescribing a drug.

The purpose of this study is to assess the impact of training on peripheral endothelial function as measured using EndoPAT whole body-EMS for a 16-week period.