Clinical Trials

This study will evaluate the efficacy of ranolazine as compared with placebo when used as part of standard medical therapy in chronic angina subjects with incomplete revascularization post-PCI on the composite of ischemia-driven revascularization or ischemia-driven hospitalization without revascularization.

The purpose of this study is to demonstrate acute effectiveness and safety of minimally-invasive pericardiotomy in patients with Heart Failure (HFpEF).

The purpose of this study is to compare the total fluid volume of using 5% human albumin and Lactated Ringer's in the perioperative cardiac surgical patient. Our hypothesis is that the individual total fluid volume will be less with 5% human albumin compared to Lactated Ringer's in the perioperative cardiac surgical patient.

The purpose of this study is to assess the effectiveness and safety of D-PLEX administered concomitantly over a period of 90 days (3 months)with the standard of care (SOC) IV prophylactic antibiotic treatment vs. SOC in prevention of post-cardiac surgery sternal infections.

The aims of this investigation are:

To assess the predictive value (and accuracy) of clinical and physiologic preoperative variables in identifying patients at risk for the development of new-onset atrial arrhythmia after cardiac surgery.

To assess the feasibility of a physiological risk model based on clinical and echocardiographic indexes to predict post-operative AF.

To assess the role of prophylactic agents in the prevention of new-onset postoperative POAF

To assess the economic impact of new-onset postoperative AF:

• Length of hospital stay (will be measured as fractions of days)

• Hospital cost (will be measured in standardized dollars)

• Resource utilization (will be measured by resource-based relative-value units)

To assess the outcome ...