Clinical Trials

The purpose of this study is to assess the patient’s quality of life following the paravertebral block(s) day post-op, 3-day post-op, 7-day post-op, and 2 weeks post-op. Also, to assess the patient’s function following the paravertebral block(s) 1-day post-op, 3-day post-op, 7-day post-op, and 2 weeks post-op, and assess the patient’s pain level following the paravertebral block(s) day post-op, 3-day post-op, 7-day post-op, and 2 weeks post-op.

The purpose of this study is to evaluate stellate ganglion blockade with local anesthetic intraoperatively to reduce the development of postoperative atrial fibrillation.

Atrial fibrillation is an important postoperative complication following cardiac surgery despite many attempts to reduce the incidence. Temporary stellate ganglion blockade reduces ventricular arrythmias in various circumstances with animal and early human data also showing an effect on the development of atrial fibrillation. The duration of arrythmia control outlasts the expected duration of local anesthetic effect by a significant duration.  Stellate ganglion blockade has potential for great impact reducing the burden of POAF including large cost savings, reduction in ...

The purpose of this study is to analyze the effectiveness of the sphenopalatine ganglion (SPG) block with lidocaine vs. SPG block with placebo in preventing the need for epidural blood patch (EBP) in women who develop post dural puncture headache (PDPH) after accidental puncture during placement of lumbar epidural anesthesia (LEA) for labor.

The purpose of this study is to evaluate the safety and effectiveness of the Altius® System High Frequency Nerve Block (HFNB) treatment for the management of post-amputation pain.

A secondary objective is to determine the impact of Altius HFNB treatment for post-amputation pain on health outcomes, including measurement health-related quality of life and use of pain medications.

The purpose of this study is to determine the feasibility of using SSPGB to reduce the self-reported headache pain that patients with aneurysmal SAH experience during their hospital admission.

The purpose of this study is to compare intubating conditions at varying levels of rocuronium-induced neuromuscular blockade.

This study aims to investigate whether administration of vancomycin intravenously via a Bier block, typically a method for providing regional anesthesia in the upper extremity, leads to higher soft tissue and bone antibiotic concentrations compared to routine intravenous administration.  Higher tissue concentrations could be desirable for prophylaxis in complex upper extremity reconstruction, or for treatment of difficult infections.

The purpose of this study is to to demonstrate the feasibility of performing ultrasound-guided erector spinae plane blocks in the Emergency Department (ED) and Intensive Care Unit (ICU).

The purpose of this study is to compare the effectiveness of pain control between a single shot interscalene brachial plexus nerve block, a continuous interscalene brachial plexus nerve block, and a local infiltration analgesia. Total shoulder arthroplasty is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery. The use of interscalene brachial plexus nerve block remains the cornerstone for analgesia following shoulder surgery, however, there has been increasing interest in local infiltration analgesia use for total joint arthroplasty. The benefits of local infiltration analgesia within a comprehensive analgesia clinical pathway have yet to be ...

The purpose of this study is to compare the use of ultrasound guidance and nerve stimulator guidance with a popliteal (knee) nerve block for postoperative pain control.

The purpose of this study is to assess analgesia effectiveness between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty. It also aims to include pain scores and opioid consumption at pre-defined time intervals, peripheral nerve block complications, length of hospital stay, and postoperative follow-up up to 7 days after surgery.

The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

The purpose of this study is to assess the safety of the Angel® Concentrated Platelet Rich Plasma System and Angel® CPRP Processing Set to process Platelet Rich Plasma for intra-articular injection into four lumbar facet joints (2 levels) causing chronic low back pain.