Sleeve gastrectomy

Displaying 8 studies

  • Gastric Epigenome and Transcriptome in Humans Rochester, MN

    The purpose of this study is to improve our understanding of why gastrointestinal symptoms occur in diabetes mellitus patients and identify new treatment(s) in the future.  

    These symptoms are often distressing and may impair glycemic control. We do not understand how diabetes mellitus affects the GI tracy. In 45 patients undergoing sleeve gastrectomy, we plan to compare the cellular composition of circulating peripheral mononuclear cells, stomach immune cells, and interstitial cells of Cajal in the stomach. 

     

  • Post-Market Surveillance With a Novel mHealth Platform Rochester, MN

    This is a study to pilot the feasibility of using a novel patient-led, smartphone-based mobile health platform (Hugo) for real-world surveillance of outcomes of patients after sleeve gastrectomy and catheter-base atrial fibrillation ablation.

  • Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction Rochester, MN

    The purpose of this study is to identify a predictive model for worsening of preexisting gastroesophageal reflux disease (GERD) or development of de novo GERD after laparoscopic sleeve gastrectomy (LSG) by using EndoFLIP, upper endoscopy and esophageal manometry to assess patients preoperatively in a discovery cohort.  This prospective predictive model will then identify sensitivity, specificity, positive and negative predictive values for prediction of worsening or de novo GERD.

  • Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes Jacksonville, FL

    The objectives of this study are to identify circulating extracellular vesicle (EV)-derived protein and RNA signatures associated with Type 2 Diabetes (T2D), and to identify changes in circulating EV cargo in patients whose T2D resolves after sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).

  • Quality of Life after Endoscopic Bariatric Therapies Rochester, MN

    The purpose of this study is to investigate the change in quality of life after endoscopic bariatric therapies and to correlate the changes in quality of life with changes in weight after endoscopic bariatric Therapies (EBTs).

  • Comparison of the Diagnostic Accuracy of Fujifilm Endoscopic Hypoxia Imaging (FEHI) to Indocyanine Green Fluorescein Imaging in Assessing Intraoperative Tissue Ischemia in Gastrointestinl Surgery Jacksonville, FL

    The aims of this study are to compare the diagnostic accuracy of FEHI, a non-invasive, non-drug, spectral imaging technology to current standard of care, ICG fluorescein imaging, with regard to intraoperative tissue ischemia, to estimate the optimal threshold value for SpO2 in FEHI to achieve optimal correlation with ICG imaging, and to compare the time needed to complete FEHI compared to ICG. These will be compared in the final 70% of cases to avoid learning curve bias on the first cases.

  • A StudyUsing Telemedicine Care to Determine What Bariatric Patients Prefer Rochester, MN

    The primary purpose of this study is to determine bariatric patients’ preference of telemedicine or in-person assessment for post-operative care.

  • Pharmacogenomics and Post-Operative Nausea and Vomiting Rochester, MN

    The Researchers overall goal is to evaluate the benefit and utility of preemptive genotypic data to guide post-operative nausea and vomiting treatment in the bariatric surgical population. The hypothesis is that using genotypic variation in CYP2D6 to select the appropriate 5HT3 serotonin receptor antagonist to treat PONV will decrease rates of PONV in the bariatric surgical population.

.

Mayo Clinic Footer