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Regional and Seasonal Variations in the Incidence and Causative Organisms for Post-traumatic Wound infections and Osteomyelitis After Open Fractures
Rochester, MN
Preliminary indicates that there is a significant seasonal and regional variation in incidence and causative organisms for post traumatic wound infections after open fractures. This finding makes the current use of a generic antibiotic for prophylaxis suboptimal. In order to validate this original finding we need to conduct a large scale study to determine if the patterns of infection truly vary depending on the time of year and the region in which the fracture occurs, and if so to change the way prophylactic antibiotic use is administered.
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Wound Necrosis in Lower Extremity Surgery
Rochester, MN
Researchers are performing this study to evaluate if intraoperative angiography can be shown numerically to determine which wounds are at high risk of wound necrosis/breakdown.
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Use of a Collagen Membrane for Soft Tissue Grafting
Rochester, MN
Is PriMatrix wound dressing capable of regenerating gum tissue inside the mouth?
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Next Science Wound Gel Efficacy in Chronic Wound Versus Standard of Care
Jacksonville, FL
This is a 3 to 4 months, single site, prospective randomized clinical study of patients diagnosed with a chronic wound. The primary objective is to assess changes in healing rate, by measuring differences in wound area when treating chronic wounds with the Next Science Wound Gel compared to the Triple Antibiotic Ointment Neosporin (Standard of Care, SOC).
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A Study of an Electronic Patient-Reported Outcome (ePRO) Monitoring and Alert System to Improve Post-surgical Pain Self-management
Scottsdale/Phoenix, AZ; Jacksonville, FL; Rochester, MN
The purpose of this study is to test an automated alert function of an ePRO monitoring and reporting tool for use in post-surgical pain self-management.
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A Study to Evaluate the Effectiveness of Vacuum-Assisted Dressings for the Management of Open Chest Wounds
Jacksonville, FL
The purpose of this study is to evaluate the effectiveness of Vacuum-assisted dressings for treating patients who have open chest wounds by comparing the time-to-closure of such wounds to traditional wound care management.
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Breast Education through Simulation Training (BEST): Post-Mastectomy Wound and Drain Care Patient Education
Rochester, MN
Plan to conduct a pilot randomized controlled trial to determine the feasibility, benefits and educational impact of using simulation for patient education (SimEd) for post-mastectomy wound and drain care, compared to current patient education practice (StdEd). This study also seeks to derive and validate a skills assessment tool specifically developed to evaluate skills acquired during the education process and compare the results of SimEd vs StdEd; we also plan to relate the scores of our assessment tool to a validated instrument that measures readiness for patient dismissal and compare their results in both study arms.
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A Study to Determine the Safety of PEP in Skin Graft Wounds
Rochester, MN
The purpose of this study is to evaluate the safety of PEP in skin graft wounds.
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Absorbable versus Non-Absorbable Suture in Patients Undergoing Carpal Tunnel and Trigger Finger Wound Closure
Rochester, MN
The purpose of this study is to describe potential cosmetic differences in wound healing between absorbable and non-absorbable suture for wound closure of open carpal tunnel release and trigger finger pulley release, and to compare the two methods of wound closure based upon patient satisfaction, residual scar tenderness, and post-operative complications.
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A Study to Evaluate Wound Infiltration with Liposomal Bupivacaine in Laparotomy for Gynecological Malignancy
Rochester, MN
The purpose of this study is to determine whether or not there is a benefit to adding opioid injection around the spinal cord ( intrathecal) to incisional long-acting local anesthetic (liposomal bupivacaine) injection for pain management after abdominal surgery for gynecological cancer.
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A Study to Evaluate Cancer Patients' Experience with Bevacizumab- induced, Wound-healing Complications
Rochester, MN
The purpose of this study is to characterize the experiences and psychosocial impact of bevacizumab-wound-healing toxicities in cancer patients.
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A Study to Assess Wound Closure Techniques in Primary Spine Surgery Using SPY Intra-operative Angiography
Rochester, MN
The purpose of this study is to assess wound perfusion at the site of closure in primary spine surgery between running subcuticular suture, interrupted vertical mattress suture, and staple closure techniques.