Research Images
Dr. Mukhopadhyay's lab uses wild-type and knockout murine models and zebrafish models to study how proteins affect vascular permeability, angiogenesis and heart morphology. The models allow our research team to gain a better understanding of vascular permeability by monitoring it in real time. Here, explore related research images.
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Vascular permeability
This image shows the effect of dopamine on vascular permeability as induced by bradykinin (BK), platelet-activating factor (PAF) and vascular permeability factor/vascular endothelial growth factor (VPF/VEGF).
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Heart morphology
This image shows the heart morphology of wild-type mice (left) and smooth muscle protein 22-NRP1 knockout mice (right). The knockout mice are deficient in NRP1 in cardiomyoctyes and smooth muscle cells and show enlarged right ventricles.
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Echocardiography
This image shows echocardiography of wild-type mice (left) and smooth muscle protein 22α-NRP1 knockout mice (right).
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Head vessels
This is a confocal image of the head vessels of a 3-day-old Fli:GFP zebrafish embryo, showing a lateral view, anterior to posterior.
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Intersegmental vessels
This is a confocal image of intersegmental vessels of a 3-day-old zebrafish embryo.
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Microangiogram
This image, taken with Zeiss axio observer Z1, shows a microangiogram of a 3-day-old zebrafish embryo.
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Cas9 expression
This is a representative image of a 4-day-old zebrafish embryo expressing cas9 in its heart.