Research projects

The Breast Cancer SPORE supports three translational research projects:

Project 1: The Influence of Variants in ER-Positive Breast Cancer Predisposition Genes on Breast Cancer Risk and Response to Therapy is investigating genetic mutations so people can receive accurate information about their cancer risk.
Project 2: Improving the Endocrine Management of Premenopausal ER+/HER2- Breast Cancer is developing a drug called Z-endoxifen to treat premenopausal estrogen receptor-expressing breast cancer.
Project 4: P95HER2, Antitumor Immunity and the Efficacy of HER2-Directed Antibody Drug Conjugates is studying p95HER2 for better treatment options in HER2+ breast cancer.

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