| Disease or condition |
Product or technology |
Trial name and link |
Principal investigator |
| Cancer — hematologic |
Chimeric antigen receptor (CAR)-T cell therapy |
CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies |
Saad J. Kenderian, M.B., Ch.B. |
| Cancer — hematologic |
CAR-T cell therapy |
Safety and Efficacy of B-cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells in Subjects With Relapsed or Refractory BAFFR-Expressing B-cell Hematologic Malignancies |
Mohamed A. Kharfan Dabaja, M.D., M.B.A. |
| Cancer — liver |
Dendritic cells |
A Study of Intratumoral Injection of Dendritic Cells After High-Dose Conformal External Beam Radiotherapy in Patients With Unresectable Liver Cancer |
Lewis R. Roberts, M.B., Ch.B., Ph.D. |
| Cancer — reproductive |
Dendritic cells |
FrαDcs or Placebo for Patients With Advanced Stage Ovarian Cancer |
Matthew S. Block, M.D., Ph.D.;
Gerardo Colon-Otero, M.D.;
Nina J. Karlin, M.D.
|
| Cancer — reproductive |
Dendritic cells |
Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer (FRAPPE) |
Matthew S. Block, M.D., Ph.D.;
Gerardo Colon-Otero, M.D.;
Brenda J. Ernst, M.D.
|
| Cancer — reproductive |
Muc1 T cells |
Autologous, MUC1-Activated T Cells Expanded From Peripheral Blood in Patients With Relapsed and Resistant Ovarian Cancer |
Brenda J. Ernst, M.D. |
| Cancer — solid tumor |
Peptide vaccine |
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors, The PNeoVCA Study |
Yanyan Lou, M.D., Ph.D. |
| Cardiovascular disease |
Allogeneic adipose MSCs |
A Study To Evaluate Mesenchymal Stem Cells for Reducing Anastomotic Stenosis |
Sam Farres, M.D. |
| Crohn’s disease |
Autologous adipose MSCs plus matrix |
A Study To Analyze AVB-114 To Treat Complex Crohn’s Perianal Fistulas in Subjects with Quiescent Rectal Disease |
Jana G. Al Hashash, M.D., M.S.;
Justin T. Brady, M.D.;
Konstantinos A. Papadakis, M.D.
|
| Epilepsy |
Allogenic adipose MSCs |
Allogenic Adipose-Derived Mesenchymal Stem Cells for Epilepsy During Deep Brain Stimulation Surgery |
Sanjeet S. Grewal, M.D. |
| Joint damage — lumbar |
Allogeneic bone marrow MSCs |
Allogeneic, Culture-Expanded Bone Marrow-Derived Mesenchymal Stem Cells To Treat Painful Lumbar Facet Joint Arthropathies |
Wenchun Qu, M.D., Ph.D. |
| Multiple system atrophy |
Autologous adipose MSCs |
A Study To Evaluate Mesenchymal Stem Cells To Treat Multiple System Atrophy |
Wolfgang Singer, M.D. |
| Transplant — kidney |
Allogeneic adipose MSCs |
Adipose-Derived MSC To Treat Rejection in Kidney Transplant Recipients |
Timucin Taner, M.D., Ph.D. |
| Ulcerative colitis |
Autologous adipose MSCs |
A Study To Evaluate Intra-Arterial Delivery of Mesenchymal Stem Cells for Luminal Ulcerative Colitis |
William A. Faubion Jr., M.D. |