Clinical Trials

Mayo Clinic offers a variety of clinical trials that are open for enrollment to participants who want to volunteer for research studies exploring regenerative medicine therapy.

Part of Mayo Clinic's commitment to its patients involves conducting medical research that can help people live longer, healthier lives. Clinical trials are research studies that involve volunteer participants. These studies help physician-scientists better understand, diagnose, treat, and prevent diseases and conditions.

Mayo Clinic's clinical trials related to regenerative medicine include studies on amytrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), congenital heart disease, diabetic kidney disease, Parkinson's disease, osteoarthritis and many more. Mayo Clinic also has thousands of other active clinical trials and research studies, and it coordinates national and international clinical trials with other medical institutions from around the world.

• Find open clinical trials related to regenerative medicine therapy.
• Explore all clinical trials at Mayo Clinic. You can browse trials categorized by disease or condition or by procedure, or can use specific search terms and filter results by location, study status, gender, study phase and more.
• Learn about volunteering in a clinical trial.

RECLAIM Expanded Access Policy

Mayo Clinic sponsor-investigator Daniel B. F. Saris, M.D., Ph.D., has been granted Regenerative Medicine Advanced Therapy (RMAT) designation by the U.S. Food and Drug Administration (FDA) for REcycled CartiLage Auto/Allo IMplantation (RECLAIM), a combination of autologous recycled chondrons and allogeneic adipose-derived mesenchymal stromal cells manufactured by the Mayo Clinic Center for Regenerative Biotherapeutics in Rochester, Minnesota, for symptomatic focal cartilage defects of the knee.

In accordance with section 561A(f)(2) of the Federal Food, Drug and Cosmetic Act (FD&C Act), Mayo Clinic is providing a public disclosure of the Expanded Access Policy for RECLAIM.

Currently, RECLAIM is not being made available on an expanded access basis. Additional information regarding the associated investigational new drug (IND) clinical trial can be accessed on clinicaltrials.gov.

For questions regarding this Expanded Access Policy, contact mailto:regenmed@mayo.edu.

Mayo Clinic may revise this policy at any time.