Leading cardiac regeneration discovery, translation and application
Overview
Unprecedented hope
Cardiovascular disease, the leading cause of premature death around the world, is on the rise. Traditional medical therapies are not able to fully address the burden of heart disease, and the shortage of organs available for transplantation remains a key barrier for offering solutions to millions of patients across the globe.
Through the visionary leadership and generous philanthropy of Russell and Kathy Van Cleve, unprecedented hope is beginning to translate into future healing options for those with heart disease.
By harnessing the body's natural ability to heal, regenerative medicine is addressing the unmet needs of patients with chronic or complex conditions who often have no other viable treatment options.
Broad impact
The goal of the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program is to advance stem cell therapies, cell-free regeneration and tissue engineering. To do this, the program accelerates the discovery, translation and application of innovative regenerative products for heart disease.
Importantly, results from this work will not only make an impact in cardiovascular health but also advance novel regenerative solutions across medical and surgical specialties to address vast unmet patient needs.
Strategic focus
Through a shared vision with Russell and Kathy Van Cleve, the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program has the goal of creating novel, affordable and accessible cardiac regenerative therapies to restore the health of people with heart disease.
After meeting the highest standards of quality control and best manufacturing practices, products undergo rigorous testing in clinical trials to ensure their safe translation to clinical practice. Finally, research findings are applied to patient care in areas such as surgery, radiology, laboratory medicine and more, fostering Mayo Clinic's regenerative care model of not only reversing chronic disease but also restoring health to individuals and their communities.
Research pillars
Research in the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program is based on three pillars of investigative focus:
Vision
Contemporary regenerative medicine is underpinned by the recognition that full regeneration ultimately restores the person as a whole. Fostering the Mayo Clinic regenerative care model, the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program is advancing not only the restoration of organ health but also the rebuilding of individuals in their communities.
Mission
The mission of the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program is to position Mayo Clinic as the premier regenerative medicine destination: leading in the discovery of novel cell-therapy platforms that address cardiac pathologies, advancing off-the-shelf cell-free therapies from the bench toward clinical cardiovascular practice and establishing cardiac tissue engineering — thereby transforming the reach of modern regenerative care.