The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

Overview

About this study

The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a potentially fatal cardiovascular event.

This study will be a retrospective and prospective review of medical course and current health of men and women with SCAD.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

* Men and women able to give informed consent
* Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD)
* SCAD in women who are pregnant or within 12 months postpartum at the time of SCAD
* SCAD in individuals who self-identify as a member of a racial or ethnic group that is currently underrepresented in the registry. This would include anyone who identifies as: Black/African American, Asian, American Indian, or Alaska Native, Native Hawaiian, or Other Pacific Islander, and any race with Hispanic ethnicity
* SCAD in a man
* SCAD in persons younger than 30 years of age
* SCAD within the past 2 weeks (acute)
* SCAD patient enrolling into any other Mayo Clinic SCAD Research Study
* SCAD in individuals who have a relative that has had a SCAD event

Exclusion Criteria:

* Lack of angiographic confirmation of SCAD
* Iatrogenic dissection or an alternate diagnosis

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/18/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Marysia Tweet, M.D., M.S.	Open for enrollment	Contact information: Susan Milbrandt C.C.R.C. (507) 266-3180 mayoscad@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Marysia Tweet, M.D., M.S.

Open for enrollment

Contact information:

Susan Milbrandt C.C.R.C.

(507) 266-3180

mayoscad@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials