Behavioral Interventions to Prevent or Delay Dementia

Overview

About this study

This study will compare the effectiveness of different combinations of 5 types of behavioral interventions across patient-centered outcomes. It will also evaluate which outcomes (e.g. quality of life, cognition, function, mood) matter most to people at risk for dementia and their care partners. The results of this study have the potential to direct patients, families, and health care providers as to which combinations of behavioral interventions provide the greatest potential impact on which dementia prevention outcomes. Greater use of behavioral strategies that are targeted to the outcomes of most important to the patient will likely improve patient compliance and treatment adherence. This, in turn, can lessen the need for medication, health care, and long term care utilization.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

A candidate for the HABIT program with a diagnosis of amnestic MCI (confirmed at eligibility visit by a Clinical Dementia Rating (CDR) scale of 0.5).
A cognitively normal care partner who has at least twice-weekly contact with the participant.
Either not taking or stable on memory medicine(s) (e.g. donepezil) for at least 3 months.
Fluent in English. (Expanding the program to communities of Spanish- speakers will be a high priority in subsequent dissemination work).

Exclusion Criteria:

Inclusion in another clinical trial that would exclude participation. Subject will be considered for participation at the end of such a trial or as appropriate.
Medically unable to participate in all arms by virtue of visual or auditory impairments or non-ambulatory status.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Julie Fields, Ph.D., L.P.	Closed for enrollment	Contact information: Sherrie Hanna M.A., L.P. (507)538-8341 Hanna.Sherrie@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Julie Fields, Ph.D., L.P.	Closed for enrollment	Contact information: Miranda Morris (904)953-2677 Morris.Miranda@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Julie Fields, Ph.D., L.P.	Closed for enrollment	Contact information: Teresa Radam CCRP (480)342-3775 radam.teresa@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Julie Fields, Ph.D., L.P.

Closed for enrollment

Contact information:

Sherrie Hanna M.A., L.P.

(507)538-8341

Hanna.Sherrie@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Julie Fields, Ph.D., L.P.

Closed for enrollment

Contact information:

Miranda Morris

(904)953-2677

Morris.Miranda@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Julie Fields, Ph.D., L.P.

Closed for enrollment

Contact information:

Teresa Radam CCRP

(480)342-3775

radam.teresa@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials