Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation

Overview

About this study

Does dual hemispheric stimulation of the subthalamic nucleus (STN) and fornix/hypothalamus potentially improve cognitive function in patients with Parkinsons disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

All patients will be enrolled from the practice of the primary investigator.
PD patients in whom optimal medical therapy has failed.
All patients will have responsivity to levodopa.
Individuals with normal or mild cognitive impairment.

Exclusion Criteria:

Clinically significant dementia
Other significant neurological or psychiatric disease
Previous brain surgery including pallidotomy or thalamotomy
Previous placement of other implantable devices

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Jacksonville, Fla. Mayo Clinic principal investigator Ryan Uitti, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Jacksonville, Fla.

Mayo Clinic principal investigator

Ryan Uitti, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials